← All insights

Insights · Niacinamide

Niacinamide, what a 12-week study showed

· 2 min read

Niacinamide

Did you know that a 5% niacinamide cream was associated with fewer fine lines and more elastic skin in 12 weeks?

A vitamin for the skin

Niacinamide is a form of vitamin B3. In recent years it has become one of the most common ingredients in cosmetics, valued because it is generally well tolerated. Earlier studies had already observed improvements in the appearance of dark spots and redness on the face.

The researchers wanted to find out whether niacinamide applied to the skin also affects other visible signs of aging, such as fine lines, sallowness and elasticity.

How the study was done

In the study, published in 2005, 50 women with signs of facial photoaging applied a 5% niacinamide cream to one half of the face twice a day for 12 weeks. On the other half they applied the same cream without niacinamide.

The half to be treated was chosen at random, and neither the participants nor the researchers knew which it was, in a double-blind design. Facial images and instrumental measurements, including elasticity, were collected at the start and then every four weeks.

What was observed

On the half of the face treated with niacinamide, there was a reduction in the appearance of wrinkles and fine lines, dark spots, red blotchiness and sallowness, the yellowish tone of the skin. Skin elasticity, measured with an instrument called a cutometer, improved.

The authors conclude that, in addition to the benefits already observed, topical niacinamide is also associated with a better appearance of wrinkles and skin tone and with improved elasticity.

How to read the result

Comparing two halves of the same face is a good way to reduce differences between people, and the double-blind design limits the expectations of both participants and assessors. Twelve weeks is a reasonable period for seeing changes in the appearance of the skin.

The study did involve a specific group, 50 fair-skinned women with signs of photoaging, and one specific formula. The results cannot be automatically applied to other skin types or other concentrations. If you are thinking of adding niacinamide to your routine, especially alongside other active ingredients, ask a dermatologist for advice.

This article is for information only. It does not replace the advice of a doctor or dermatologist, whom you should consult with any question about your skin.

Let’s talk

Do you have a question about your skin?

Write to us. The Clair Clinique team will be happy to answer, whether it is about this study, your routine or a personalized consultation.